About Me
Bridging computational innovation with production-ready genomic solutions
I'm a PhD candidate in Human Genetics at Vanderbilt University, specializing in large-scale computational genomics and cloud infrastructure. My work focuses on understanding the genetic architecture of immune cell variation across diverse populations.
With experience spanning clinical diagnostics at the New York Genome Center and research at leading academic institutions, I bridge CLIA-certified clinical workflows with cutting-edge research methodologies. I've developed and deployed production-grade pipelines that have processed over 1 million whole genome sequences across major biobanks including All of Us, UK Biobank, and TOPMed.
My approach combines rigorous statistical genetics with scalable cloud computing, enabling discoveries that translate to real-world health impacts. As a first-author in Nature Communications and contributor to multiple high-impact studies, I'm driven by the potential of genomics to transform our understanding of human health and disease.
Experience
From clinical diagnostics to research innovation
- Architected cloud-native pipelines processing 1M+ genomes across All of Us, UK Biobank, and TOPMed
- Built production-ready genetic association testing infrastructure for 1.1M+ WGS samples
- Led multi-ancestry GWAS studies identifying genetic determinants of immune cell fractions
- Developed single-cell DNA somatic variant analysis framework applied to 1,000+ cells
- Mentored laboratory members on cloud computing and facilitated Terra/All of Us onboarding
- Engineered production pipelines for clinical WGS with CLIA certification
- Led validation of NovaSeq workflow transition with comprehensive benchmarking
- Developed custom tools streamlining variant curation for medical directors
- Maintained compliance with New York State regulatory standards
- Developed comprehensive IBD analysis software for diverse populations
- Conducted GWAS of height in Latino populations for HCHS/SOL consortium
- Analyzed population structure in UK Biobank cohort
Technical Expertise
Breadth and depth across genomics, stats, and infrastructure
Research & Publications
Selected works and manuscripts
Identified genetic variants influencing immune cell composition across diverse populations, with implications for autoimmune disease and infection susceptibility.
DOI: 10.1038/s41467-024-51095-1Education
- Advisors: Alexander G. Bick, MD, PhD and Nancy J. Cox, PhD
- Focus: Population genomics, immune genetics, cloud-scale computational infrastructure
Get in touch
Open to roles in biotech, pharma, and research
